RESEARCH

We are a neurobiology lab interested in studying the assembly and function of primary cilia – specialized signaling hubs that extend from the surface of most cells in the human body. Primary cilia play essential roles during development, and defects in cilia assembly or function cause genetic disorders called ciliopathies. We use sophisticated molecular genetics, proteomics, and live imaging approaches in C. elegans with complementary studies in human cells to identify new genes and map signaling networks that regulate cilia assembly and remodeling.